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Scientists have completely cured type 2 diabetes for the first time: how they did it

Date: July 14, 2024 Time: 13:57:37

Researchers from China reported that for the first time they managed to completely cure type 2 diabetes in a 59-year-old man with 25 years of experience with this disease.

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Researchers from China reported that for the first time they managed to completely cure type 2 diabetes in a 59-year-old man with 25 years of experience with this disease. He underwent a groundbreaking cell transplant in 2021 and has not received medication since 2022. Have the Chinese revolutionized medicine? Komsomolskaya Pravda studied the case together with immunologist, candidate of medical sciences and general director of a contract research company, Nikolai Kryuchkov.

HOW DOES IT WORK?

The man was transplanted with laboratory-created pancreatic cells that produce insulin and control blood sugar levels. The man’s own stem cells were used. Under the influence of a special chemical cocktail, healthy cells of the pancreas were grown from stem cells – an organ that, among other functions, produces insulin (with its help our body regulates the amount of sugar in the blood).

A 59-year-old man was implanted with 1.2 million new pancreatic cells (beta cells from the islets of Langerhans). This made the pancreas, which was practically out of commission, work. At least in the horizon of 1 year and 3 months, significant improvements are visible.

The researchers suggest that by implanting these cells it will be possible to restore the pancreas’ ability to produce its own insulin in other people with diabetes.

THE METHOD HAS A SERIOUS SIDE

First, although these cells look like healthy human pancreatic cells (a phenotype), they are still different.

Therefore, not everyone puts down roots. And even if they take root, the effect is not enough to completely abandon insulin treatment. There are certainly benefits: smaller doses of external insulin are needed. In addition, a more fluid dynamics of insulin production is established in the body. But this cannot be considered a cure, says Nikolai Kryuchkov.

Secondly, if we talk about people with type 1 diabetes (they would especially need such technology), then their body begins to recognize these “healing” cells as foreign and gradually begins to destroy them. And, as a rule, it is not possible to overcome such a reaction.

Thirdly, when we use this type of cellular technologies, there is a risk of tumorigenesis, that is, the risk of degeneration into a tumor, says Nikolai Kryuchkov. And this side effect has been confirmed several times.

– Although this is the initial part of the research, they showed us how the technology works in humans. We have verified that this treatment is possible and that it has short and medium term effects. It is important. But can this be called a cure for diabetes? It is still doubtful,” says Nikolai Kryuchkov. – A longer observation period is needed. The most interesting thing is to see if this is suitable for people with type 1 diabetes. In any case, even if a significant effect occurs in patients with advanced type 2 diabetes, this will already be an advance for medicine.

HOW SOON WILL TECHNOLOGY REACH THE MASSES?

Insulin injection is an affordable treatment method (this is its advantage), but not the most suitable from a physiological point of view, the expert points out. The body still suffers because of this therapy. Therefore, the new technology can potentially reduce the risks of disability: damage to vision, nervous system, blood vessels, kidneys and heart.

And one more warning: it is a very expensive technology, literally several groups of scientists work in this area in the world.

– But if the effectiveness of the method is demonstrated, the technology will subsequently be improved and production costs will be lowered. It will take ten years before it will be possible to use the technology, although not en masse, but in individual medical centers,” says Nikolai Kryuchkov.

* This website provides news content gathered from various internet sources. It is crucial to understand that we are not responsible for the accuracy, completeness, or reliability of the information presented Read More

Puck Henry
Puck Henry
Puck Henry is an editor for ePrimefeed covering all types of news.
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